Position Summary: 

Enanta Pharmaceuticals is a chemistry-driven biotech located in Watertown, MA that focuses on viral and liver diseases in areas of highly unmet medical needs. We are seeking highly motivated and productive Organic Medicinal Chemists to synthesize target molecules for exciting early-stage drug discovery projects. 

Primary Duties and Responsibilities:
  • Design, plan and execute multi-step organic synthesis and purification of high-quality target molecules for biological screening.
  • Participate in brainstorming and contribute new proposals and ideas.
  • Interact with colleagues in biology, pharmacology, and DMPK groups.
  • Analyze SAR according to biological, pharmacological and toxicological findings.
  • Prioritize the chemistry efforts to ensure timeline adherence and project alignment to meet group and company goals.
  • Work cross-functionally with counterparts in process chemistry and CMC groups.
  • Assist in the preparation of patents, publications, and project planning.

General Qualifications:
  • Collaboration & Teamwork: Relates to employees and management in a cooperative manner that helps others to achieve their best.
  • Productivity/Organizing/Planning: Meets deadlines, demonstrates effective use of time, and handles multiple assignments simultaneously.
  • Communication Skills: The ability to convey both written and verbal information effectively and efficiently.
  • Willingness to Acknowledge Areas for Growth: Understands need for growth and is receptive to constructive feedback.
  • Detail-Oriented: Follows precise procedures and demonstrates thoroughness in performing job tasks and assignments.    

Education, prior work experience, and specialized skills and knowledge:
  • Ph.D. in synthetic organic chemistry, medicinal chemistry, or physical organic chemistry is required
  • Candidates with 0-5 years of experience either as a postdoc or within the bio/pharma industry will be considered
  • Sound knowledge of organic chemistry principles
  • Work efficiently and productively in a highly dynamic team environment
  • Excellent interpersonal and communication skills

How to Apply

Please complete the application below and include the following attachments:

  • Cover Letter
  • CV / Resume
  • Research Summary (if applicable)
About Enanta

Enanta Pharmaceuticals is using its robust, chemistry-driven approach and drug discovery capabilities to become a leader in the discovery and development of small molecule drugs for the treatment of viral infections and liver diseases. Enanta’s research and development efforts are currently focused on the following disease targets: respiratory syncytial virus (RSV), non-alcoholic steatohepatitis (NASH)/ primary biliary cholangitis (PBC), and hepatitis B virus (HBV).  Please visit www.enanta.com for more information.

Enanta’s research and development activities are currently funded by royalties from HCV products developed under its collaboration with AbbVie.  Glecaprevir, a protease inhibitor discovered by Enanta, is now sold by AbbVie in numerous countries as part of its newest treatment for chronic hepatitis C virus (HCV) infection. This leading HCV regimen is sold under the tradenames MAVYRET™ (U.S.) and MAVIRET™ (ex-U.S.) (glecaprevir/pibrentasvir).

Enanta is located in Watertown, MA, just minutes from Harvard, MIT, and downtown Boston. We offer a competitive compensation program and a comprehensive employee benefits package. For more details, see our Careers page.

Enanta Pharmaceuticals is an equal opportunity employer (EOE) with a commitment to diversity. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to race, color, national origin, age, religious creed, gender, gender identity, sexual orientation, physical or mental disability, protected veteran status, or any other class protected by law.

Visit Careers at Enanta Pharmaceuticals

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